MESDC2
Reactivité: Humain
WB, IHC, ELISA, ICC, IF
Hôte: Lapin
Polyclonal
PE
Indications d'application
WB,1:500 - 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
MESDC2
(Mesoderm Development Candidate 2 (MESDC2))
Autre désignation
MESDC2
Sujet
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs. Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ formation by promoting cell-surface expression of LRP4 (By similarity. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE cells (By similarity.,MESDC2,BOCA,MESD,Cell Biology & Developmental Biology,Stem Cells,Mesenchymal Stem Cells,MESDC2