METTL13 anticorps (AA 430-699)

N° du produit ABIN6143755

Cet anticorps anti-METTL13 est un anticorps Lapin Polyclonal détectant METTL13 dans WB et IF. Adapté pour Humain.

Aperçu rapide pour METTL13 anticorps (AA 430-699) (ABIN6143755)

Antigène: METTL13 (Methyltransferase Like 13 (METTL13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp METTL13 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-METTL13 anticorps

Épitope: AA 430-699

Séquence: LKDVSHKAQK KRKKDRKKQR PADAEDLPAA PGQSIDKSYL CCEHHKAMIA GLALLRNPEL LLEIPLALLV VGLGGGSLPL FVHDHFPKSC IDAVEIDPSM LEVATQWFGF SQSDRMKVHI ADGLDYIASL AGGGEARPCY DVIMFDVDSK DPTLGMSCPP PAFVEQSFLQ KVKSILTPEG VFILNLVCRD LGLKDSVLAG LKAVFPLLYV RRIEGEVNEI LFCQLHPEQK LATPELLETA QALERTLRKP GRGWDDTYVL SDMLKTVKIV

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 430-699 of human METTL13 (NP_057019.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur METTL13

Antigène: METTL13 (Methyltransferase Like 13 (METTL13))

Autre désignation: METTL13

Sujet: Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2 at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55'. Has no activity towards core histones H2A, H2B, H3 and H4. Negatively regulates cell proliferation at G1/S transition via transcriptional suppression of cell cycle regulatory genes such as CDK4 and CDK6.,METTL13,5630401D24Rik,CGI-01,KIAA0859,feat,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,METTL13

Poids moléculaire: 44 kDa/61 kDa/68 kDa/72 kDa/78 kDa

ID gène: 51603

UniProt: Q8N6R0