EFHA1 anticorps (AA 50-150)

N° du produit ABIN6143833

Détail du produit anti-EFHA1 anticorps

Antigène: EFHA1 (EF-Hand Domain Family, Member A1 (EFHA1))

Épitope: AA 50-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EFHA1 est non-conjugé

Application: Western Blotting (WB)

Séquence: AWHHSRVSVA ARDGSFTVSA QKNVEHGIIY IGKPSLRKQR FMQFSSLEHE GEYYMTPRDF LFSVMFEQME RKTSVKKLTK KDIEDTLSGI QTAGCGSTFF R

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 50-150 of human MICU2 (NP_689939.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EFHA1

Antigène: EFHA1 (EF-Hand Domain Family, Member A1 (EFHA1))

Autre désignation: MICU2 (EFHA1 Produits)

Synonymes: anticorps 1110008L20Rik, anticorps EFHA1, anticorps Efha1, anticorps RGD1309934, anticorps Smhs2, anticorps 4833427E09Rik, anticorps AU041871, anticorps mitochondrial calcium uptake 2, anticorps MICU2, anticorps Micu2

Sujet: Key regulator of mitochondrial calcium uniporter (MCU required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering.,MICU2,1110008L20Rik,EFHA1,Cell Biology & Developmental Biology,MICU2

Poids moléculaire: 49 kDa

ID gène: 221154

UniProt: Q8IYU8