EFHA1 anticorps (AA 50-150)
Aperçu rapide pour EFHA1 anticorps (AA 50-150) (ABIN6143833)
Antigène
Voir toutes EFHA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 50-150
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Séquence
- AWHHSRVSVA ARDGSFTVSA QKNVEHGIIY IGKPSLRKQR FMQFSSLEHE GEYYMTPRDF LFSVMFEQME RKTSVKKLTK KDIEDTLSGI QTAGCGSTFF R
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 50-150 of human MICU2 (NP_689939.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- EFHA1 (EF-Hand Domain Family, Member A1 (EFHA1))
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Autre désignation
- MICU2
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Sujet
- Key regulator of mitochondrial calcium uniporter (MCU required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering.,MICU2,1110008L20Rik,EFHA1,Cell Biology & Developmental Biology,MICU2
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Poids moléculaire
- 49 kDa
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ID gène
- 221154
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UniProt
- Q8IYU8
Antigène
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