MMP13 anticorps (AA 262-471)

N° du produit ABIN6143903

Cet anticorps anti-MMP13 est un anticorps Lapin Polyclonal détectant MMP13 dans WB et IF. Adapté pour Humain.

Aperçu rapide pour MMP13 anticorps (AA 262-471) (ABIN6143903)

Antigène: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP13 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-MMP13 anticorps

Épitope: AA 262-471

Séquence: IQSLYGPGDE DPNPKHPKTP DKCDPSLSLD AITSLRGETM IFKDRFFWRL HPQQVDAELF LTKSFWPELP NRIDAAYEHP SHDLIFIFRG RKFWALNGYD ILEGYPKKIS ELGLPKEVKK ISAAVHFEDT GKTLLFSGNQ VWRYDDTNHI MDKDYPRLIE EDFPGIGDKV DAVYEKNGYI YFFNGPIQFE YSIWSNRIVR VMPANSILWC

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 262-471 of human MMP13 (NP_002418.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MMP13

Antigène: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Autre désignation: MMP13

Sujet: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11.,MMP13,CLG3,MANDP1,MDST,MMP-13,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,Cardiovascular,Angiogenesis,MMP13

Poids moléculaire: 53 kDa

ID gène: 4322

UniProt: P45452