MORF4L2 anticorps (AA 1-100)

N° du produit ABIN6143950

Cet anticorps anti-MORF4L2 est un anticorps Lapin Polyclonal détectant MORF4L2 dans WB, IHC et IF. Adapté pour Humain.

Aperçu rapide pour MORF4L2 anticorps (AA 1-100) (ABIN6143950)

Antigène: MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MORF4L2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MORF4L2 anticorps

Épitope: AA 1-100

Séquence: MSSRKQGSQP RGQQSAEEEN FKKPTRSNMQ RSKMRGASSG KKTAGPQQKN LEPALPGRWG GRSAENPPSG SVRKTRKNKQ KTPGNGDGGS TSEAPQPPRK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MORF4L2 (NP_001135890.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MORF4L2

Antigène: MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))

Autre désignation: MORF4L2

Sujet: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.,MORF4L2,MORFL2,MRGX,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Endocrine & Metabolism,MORF4L2

Poids moléculaire: 32 kDa

ID gène: 9643

UniProt: Q15014

Pathways: Regulation of Muscle Cell Differentiation