MTF2 anticorps (AA 1-190)

N° du produit ABIN6144136

Cet anticorps anti-MTF2 est un anticorps Lapin Polyclonal détectant MTF2 dans WB. Adapté pour Humain.

Aperçu rapide pour MTF2 anticorps (AA 1-190) (ABIN6144136)

Antigène: MTF2 (Metal Response Element Binding Transcription Factor 2 (MTF2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTF2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MTF2 anticorps

Épitope: AA 1-190

Séquence: MRDSTGAGNS LVHKRSPLRR NQKTPTSLTK LSLQDGHKAK KPACKFEEGQ DVLARWSDGL FYLGTIKKIN ILKQSCFIIF EDSSKSWVLW KDIQTGATGS GEMVCTICQE EYSEAPNEMV ICDKCGQGYH QLCHTPHIDS SVIDSDEKWL CRQCVFATTT KRGGALKKGP NAKALQVMKQ TLPYSVADLE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MTF2 (NP_001157864.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MTF2

Antigène: MTF2 (Metal Response Element Binding Transcription Factor 2 (MTF2))

Autre désignation: MTF2

Sujet: Polycomb group (PcG protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3 and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity. Regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation (By similarity. Promotes recruitment of the PRC2 complex to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells (By similarity. Required to repress Hox genes by enhancing H3K27me3 methylation of the PRC2 complex (By similarity. In some conditions may act as an inhibitor of PRC2 activity: able to activate the CDKN2A gene and promote cellular senescence by suppressing the catalytic activity of the PRC2 complex locally (By similarity. Binds to the metal-regulating-element (MRE of MT1A gene promoter (By similarity.,MTF2,M96,PCL2,TDRD19A,dJ976O13.2,Epigenetics & Nuclear Signaling,Transcription Factors,Chromatin Remodeling,MTF2

Poids moléculaire: 29 kDa/55 kDa/60 kDa/67 kDa

ID gène: 22823

UniProt: Q9Y483

Pathways: Stem Cell Maintenance