Melatonin Receptor 1A anticorps (AA 281-350)
Aperçu rapide pour Melatonin Receptor 1A anticorps (AA 281-350) (ABIN6144165)
Antigène
Voir toutes Melatonin Receptor 1A (MTNR1A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 281-350
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Séquence
- YYMAYFNSCL NAIIYGLLNQ NFRKEYRRII VSLCTARVFF VDSSNDVADR VKWKPSPLMT NNNVVKVDSV
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 281-350 of human MTNR1A (NP_005949.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Melatonin Receptor 1A (MTNR1A)
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Autre désignation
- MTNR1A
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Sujet
- This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.,MTNR1A,MEL-1A-R,MT1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Neuroscience,MTNR1A
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Poids moléculaire
- 39 kDa
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ID gène
- 4543
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UniProt
- P48039
Antigène
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