HSPB8 anticorps
Aperçu rapide pour HSPB8 anticorps (ABIN6144482)
Antigène
Voir toutes HSPB8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human HSPB8/HSP22
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000, IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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Autre désignation
- HSPB8
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Sujet
- The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22,Neurodegenerative Diseases,Neuroscience,Signal Transduction,HSPB8
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Poids moléculaire
- 22 kDa
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ID gène
- 26353
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UniProt
- Q9UJY1
Antigène
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