Nodal anticorps (AA 198-347)

N° du produit ABIN6144699

Cet anticorps Lapin Polyclonal détecte spécifiquement Nodal dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour Nodal anticorps (AA 198-347) (ABIN6144699)

Antigène: Nodal (NODAL) (Nodal Homolog (NODAL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nodal est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Nodal anticorps

Épitope: AA 198-347

Séquence: SNLSQEQRQL GGSTLLWEAE SSWRAQEGQL SWEWGKRHRR HHLPDRSQLC RKVKFQVDFN LIGWGSWIIY PKQYNAYRCE GECPNPVGEE FHPTNHAYIQ SLLKRYQPHR VPSTCCAPVK TKPLSMLYVD NGRVLLDHHK DMIVEECGCL

Réactivité croisée: Humain, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 198-347 of human NODAL (NP_060525.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Nodal

Antigène: Nodal (NODAL) (Nodal Homolog (NODAL))

Autre désignation: NODAL

Sujet: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.,NODAL,HTX5,Cell Biology & Developmental Biology,Growth factor,TGF-b-Smad Signaling Pathway,ESC Pluripotency and Differentiation,Immunology & Inflammation,Cytokines,Stem Cells,Embryonic Stem Cells,Ligand,NODAL

Poids moléculaire: 39 kDa

ID gène: 4838

UniProt: Q96S42

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of Endopeptidase Activity