OPRK1 anticorps (C-Term)

N° du produit ABIN6145043

Détail du produit anti-OPRK1 anticorps

Antigène: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OPRK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: GSTSHSTAAL SSYYFCIALG YTNSSLNPIL YAFLDENFKR CFRDFCFPLK MRMERQSTSR VRNTVQDPAY LRDIDGMNKP V

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human OPRK1 (NP_000903.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur OPRK1

Antigène: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Autre désignation: OPRK1 (OPRK1 Produits)

Synonymes: anticorps OPRK1, anticorps LOC780448, anticorps kor, anticorps KOR, anticorps OPRK, anticorps K-OR-1, anticorps KOR-1, anticorps MSL-1, anticorps Oprk2, anticorps R21, anticorps opioid receptor, kappa 1, anticorps opioid receptor kappa 1, anticorps oprk1, anticorps OPRK1, anticorps Oprk1

Sujet: This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.,OPRK1,K-OR-1,KOR,KOR-1,OPRK,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,OPRK1

Poids moléculaire: 33 kDa/42 kDa

ID gène: 4986

UniProt: P41145