OTX2 anticorps (AA 140-280)

N° du produit ABIN6145091

L’anticorps Lapin Polyclonal anti-OTX2 a été validé pour WB. Il convient pour détecter OTX2 dans des échantillons de Humain.

Aperçu rapide pour OTX2 anticorps (AA 140-280) (ABIN6145091)

Antigène: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OTX2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-OTX2 anticorps

Épitope: AA 140-280

Séquence: TPPSSTSVPT IASSSAPVSI WSPASISPLS DPLSTSSSCM QRSYPMTYTQ ASGYSQGYAG STSYFGGMDC GSYLTPMHHQ LPGPGATLSP MGTNAVTSHL NQSPASLSTQ GYGASSLGFN STTDCLDYKD QTASWKLNFN A

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 140-280 of human OTX2 (NP_068374.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur OTX2

Antigène: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Autre désignation: OTX2

Sujet: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.,OTX2,CPHD6,MCOPS5,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Neuroscience,Stem Cells,OTX2

Poids moléculaire: 31 kDa/32 kDa

ID gène: 5015

UniProt: P32243

Pathways: Dopaminergic Neurogenesis