PABPN1 anticorps (AA 1-100)

N° du produit ABIN6145153

Cet anticorps Lapin Polyclonal détecte spécifiquement PABPN1 dans WB. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour PABPN1 anticorps (AA 1-100) (ABIN6145153)

Antigène: PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PABPN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PABPN1 anticorps

Épitope: AA 1-100

Séquence: MAAAAAAAAA AGAAGGRGSG PGRRRHLVPG AGGEAGEGAP GGAGDYGNGL ESEELEPEEL LLEPEPEPEP EEEPPRPRAP PGAPGPGPGS GAPGSQEEEE

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PABPN1 (NP_004634.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-PABPN1 (ABIN6145153)

Shi, Zhang, Wu, He, Wang, Yin, Tian, Li, Cheng: "ALYREF mainly binds to the 5' and the 3' regions of the mRNA in vivo." dans: Nucleic acids research, Vol. 45, Issue 16, pp. 9640-9653, (2017) (PubMed).

Détails sur PABPN1

Antigène: PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

Autre désignation: PABPN1

Sujet: This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.,PABPN1,OPMD,PAB2,PABII,PABP-2,PABP2,Epigenetics & Nuclear Signaling,RNA Binding,PABPN1

Poids moléculaire: 31 kDa/32 kDa/37 kDa

ID gène: 8106

UniProt: Q86U42