PATZ1 anticorps (AA 250-350)

N° du produit ABIN6145252

Cet anticorps Lapin Polyclonal détecte spécifiquement PATZ1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour PATZ1 anticorps (AA 250-350) (ABIN6145252)

Antigène: PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PATZ1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PATZ1 anticorps

Épitope: AA 250-350

Séquence: PFPSVASSAP PLTGKRGRGR PRKANLLDSM FGSPGGLREA GILPCGLCGK VFTDANRLRQ HEAQHGVTSL QLGYIDLPPP RLGENGLPIS EDPDGPRKRS R

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 250-350 of human PATZ1 (NP_114440.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:4000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PATZ1

Antigène: PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))

Autre désignation: PATZ1

Sujet: The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1,22)(p36.1,q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.,PATZ1,MAZR,PATZ,RIAZ,ZBTB19,ZNF278,ZSG,dJ400N23,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,PATZ1

Poids moléculaire: 57 kDa/69 kDa/74 kDa

ID gène: 23598

UniProt: Q9HBE1