PEX19 anticorps (AA 1-299)

N° du produit ABIN6145463

Détail du produit anti-PEX19 anticorps

Antigène: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Épitope: AA 1-299

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PEX19 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MAAAEEGCSV GAEADRELEE LLESALDDFD KAKPSPAPPS TTTAPDASGP QKRSPGDTAK DALFASQEKF FQELFDSELA SQATAEFEKA MKELAEEEPH LVEQFQKLSE AAGRVGSDMT SQQEFTSCLK ETLSGLAKNA TDLQNSSMSE EELTKAMEGL GMDEGDGEGN ILPIMQSIMQ NLLSKDVLYP SLKEITEKYP EWLQSHRESL PPEQFEKYQE QHSVMCKICE QFEAETPTDS ETTQKARFEM VLDLMQQLQD LGHPPKELAG EMPPGLNFDL DALNLSGPPG ASGEQCLIM

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human PEX19 (NP_002848.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-PEX19 (ABIN6145463)

Zhou, Yu, Arshad, Wang, Lu, Gong, Gu, Li, Xu: "Coordination Among Lipid Droplets, Peroxisomes, and Mitochondria Regulates Energy Expenditure Through the CIDE-ATGL-PPARα Pathway in Adipocytes." dans: Diabetes, Vol. 67, Issue 10, pp. 1935-1948, (2018) (PubMed).

Détails sur PEX19

Antigène: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Autre désignation: PEX19 (PEX19 Produits)

Synonymes: anticorps BEST:GH03076, anticorps CG5325, anticorps DmelPex19, anticorps Dmel\\CG5325, anticorps D1S2223E, anticorps HK33, anticorps PBD12A, anticorps PMP1, anticorps PMPI, anticorps PXF, anticorps PXMP1, anticorps Pxf, anticorps PxF, anticorps Peroxin-19, anticorps Peroxin 19, anticorps Peroxisomal farnesylated protein, anticorps peroxisomal biogenesis factor 19, anticorps Pex19, anticorps Bm1_19905, anticorps PEX19

Sujet: This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.,PEX19,D1S2223E,HK33,PBD12A,PMP1,PMPI,PXF,PXMP1,Signal Transduction,PEX19

Poids moléculaire: 29 kDa/32 kDa

ID gène: 5824

UniProt: P40855