PLOD1 anticorps (AA 488-727)

N° du produit ABIN6145784

Cet anticorps Lapin Polyclonal détecte spécifiquement PLOD1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour PLOD1 anticorps (AA 488-727) (ABIN6145784)

Antigène: PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLOD1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PLOD1 anticorps

Épitope: AA 488-727

Séquence: RQQDVFMFLT NRHTLGHLLS LDSYRTTHLH NDLWEVFSNP EDWKEKYIHQ NYTKALAGKL VETPCPDVYW FPIFTEVACD ELVEEMEHFG QWSLGNNKDN RIQGGYENVP TIDIHMNQIG FEREWHKFLL EYIAPMTEKL YPGYYTRAQF DLAFVVRYKP DEQPSLMPHH DASTFTINIA LNRVGVDYEG GGCRFLRYNC SIRAPRKGWT LMHPGRLTHY HEGLPTTRGT RYIAVSFVDP

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 488-727 of human PLOD1 (NP_000293.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PLOD1

Antigène: PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))

Autre désignation: PLOD1

Sujet: Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.,PLOD1,EDS6,LH,LH1,LLH,PLOD,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,PLOD1

Poids moléculaire: 83 kDa/88 kDa

ID gène: 5351

UniProt: Q02809