RAB35 anticorps (AA 1-201)
Aperçu rapide pour RAB35 anticorps (AA 1-201) (ABIN6146576)
Antigène
Voir toutes RAB35 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-201
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Séquence
- MARDYDHLFK LLIIGDSGVG KSSLLLRFAD NTFSGSYITT IGVDFKIRTV EINGEKVKLQ IWDTAGQERF RTITSTYYRG THGVIVVYDV TSAESFVNVK RWLHEINQNC DDVCRILVGN KNDDPERKVV ETEDAYKFAG QMGIQLFETS AKENVNVEEM FNCITELVLR AKKDNLAKQQ QQQQNDVVKL TKNSKRKKRC C
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human RAB35 (NP_006852.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury." dans: Basic research in cardiology, Vol. 112, Issue 4, pp. 38, (2018) (PubMed).
: "MICAL1 controls cell invasive phenotype via regulating oxidative stress in breast cancer cells." dans: BMC cancer, Vol. 16, pp. 489, (2017) (PubMed).
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: "Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury." dans: Basic research in cardiology, Vol. 112, Issue 4, pp. 38, (2018) (PubMed).
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- RAB35 (RAB35, Member RAS Oncogene Family (RAB35))
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Autre désignation
- RAB35
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Sujet
- The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2 and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth. Together with TBC1D13 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes.,RAB35,H-ray,RAB1C,RAY,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,Cytokines,RAB35
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Poids moléculaire
- 17 kDa/23 kDa
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ID gène
- 11021
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UniProt
- Q15286
Antigène
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