RAB3IP anticorps (AA 1-150)
Aperçu rapide pour RAB3IP anticorps (AA 1-150) (ABIN6146588)
Antigène
Voir toutes RAB3IP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-150
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Séquence
- MANDPLEGFH EVNLASPTSP DLLGVYESGT QEQTTSPSVI YRPHPSALSS VPIQANALDV SELPTQPVYS SPRRLNCAEI SSISFHVTDP APCSTSGVTA GLTKLTTRKD NYNAEREFLQ GATITEACDG SDDIFGLSTD SLSRLRSPSV
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human RAB3IP (NP_071901.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- RAB3IP (RAB3A Interacting Protein (Rabin3) (RAB3IP))
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Autre désignation
- RAB3IP
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Sujet
- Guanine nucleotide exchange factor (GEF which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS, apical surface formation and lumenogenesis.,RAB3IP,RABIN3,RABIN8,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,RAB3IP
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Poids moléculaire
- 28 kDa/33-53 kDa
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ID gène
- 117177
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UniProt
- Q96QF0
Antigène
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