RCAN1 anticorps (AA 60-245)
Aperçu rapide pour RCAN1 anticorps (AA 60-245) (ABIN6146811)
Antigène
Voir toutes RCAN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 60-245
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Séquence
- DLQDLPSATI ACHLDPRVFV DGLCRAKFES LFRTYDKDIT FQYFKSFKRV RINFSNPFSA ADARLQLHKT EFLGKEMKLY FAQTLHIGSS HLAPPNPDKQ FLISPPASPP VGWKQVEDAT PVINYDLLYA ISKLGPGEKY ELHAATDTTP SVVVHVCESD QEKEEEEEME RMRRPKPKII QTRRPE
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 60-245 of human RCAN1 (NP_004405.3).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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Autre désignation
- RCAN1
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Sujet
- The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.,RCAN1,ADAPT78,CSP1,DSC1,DSCR1,MCIP1,RCN1,Signal Transduction,Neuroscience,Neurodegenerative Diseases,RCAN1
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Poids moléculaire
- 13 kDa/19 kDa/22 kDa/28 kDa
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ID gène
- 1827
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UniProt
- P53805
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Antigène
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