RUNX3 anticorps (AA 210-429)
Aperçu rapide pour RUNX3 anticorps (AA 210-429) (ABIN6147314)
Antigène
Voir toutes RUNX3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 210-429
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Séquence
- DRFGDLERLR MRVTPSTPSP RGSLSTTSHF SSQPQTPIQG TSELNPFSDP RQFDRSFPTL PTLTESRFPD PRMHYPGAMS AAFPYSATPS GTSISSLSVA GMPATSRFHH TYLPPPYPGA PQNQSGPFQA NPSPYHLYYG TSSGSYQFSM VAGSSSGGDR SPTRMLASCT SSAASVAAGN LMNPSLGGQS DGVEADGSHS NSPTALSTPG RMDEAVWRPY
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 210-429 of human RUNX3 (NP_001026850.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
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Autre désignation
- RUNX3
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Sujet
- This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.,RUNX3,AML2,CBFA3,PEBP2aC,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Apoptosis,Target gene,RUNX3
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Poids moléculaire
- 44 kDa/45 kDa
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ID gène
- 864
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UniProt
- Q13761
Antigène
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