CD81 anticorps (PE)

N° du produit ABIN614803

Détail du produit anti-CD81 anticorps (PE)

Antigène: CD81

Reactivité: Humain, Lapin, Cat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD81 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: This antibody CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Réactivité croisée (Details): Species reactivity (tested):Human, Feline (Cat), Rabbit

Immunogène: MOLT-4 (human T-ALL cell line)

Clone: M38

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE! This product is photosensitive and should be protected from light.

Stock: 4 °C

Références pour anticorps anti-CD81 (PE) (ABIN614803)

Porchet, Probst, Dráberová, Dráber, Riederer, Riederer: "Differential subcellular localization of phosphorylated neurofilament and tau proteins in degenerating neurons of the human entorhinal cortex." dans: Neuroreport, Vol. 14, Issue 7, pp. 929-33, (2003) (PubMed).

Escola, Kleijmeer, Stoorvogel, Griffith, Yoshie, Geuze: "Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." dans: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).

Imai, Kakizaki, Nishimura, Yoshie: "Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 3, pp. 1229-39, (1995) (PubMed).

Imai, Yoshie et al.: "C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and ..." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 11, pp. 6470-81, (1994) (PubMed).

Kiyotaki, Cooper, Bertoli, Kearney, Kubagawa: "Monoclonal anti-Id antibodies react with varying proportions of human B lineage cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 138, Issue 12, pp. 4150-8, (1987) (PubMed).

Détails sur CD81

Antigène: CD81

Autre désignation: CD81 / TAPA1 (CD81 Produits)

Synonymes: anticorps Tapa-1, anticorps Tapa1, anticorps Tspan28, anticorps CVID6, anticorps S5.7, anticorps TAPA1, anticorps TSPAN28, anticorps CD81 molecule, anticorps CD81 molecule b, anticorps CD81 antigen, anticorps Cd81 molecule, anticorps CD81, anticorps cd81b, anticorps Cd81

Sujet: CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells - e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.Synonyms: 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1

ID gène: 975

NCBI Accession: NP_004347

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C