SMOX anticorps (AA 1-200)
Aperçu rapide pour SMOX anticorps (AA 1-200) (ABIN6148142)
Antigène
Voir toutes SMOX AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-200
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Séquence
- MQSCESSGDS ADDPLSRGLR RRGQPRVVVI GAGLAGLAAA KALLEQGFTD VTVLEASSHI GGRVQSVKLG HATFELGATW IHGSHGNPIY HLAEANGLLE ETTDGERSVG RISLYSKNGV ACYLTNHGRR IPKDVVEEFS DLYNEVYNLT QEFFRHDKPV NAESQNSVGV FTREEVRNRI RNDPDDPEAT KRLKLAMIQQ
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human SMOX (NP_787034.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SMOX (Spermine Oxidase (SMOX))
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Autre désignation
- SMOX
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Sujet
- Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism.,SMOX,C20orf16,PAO,PAO-1,PAO1,PAOH,PAOH1,SMO,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Drug metabolism,SMOX
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Poids moléculaire
- 20 kDa/43 kDa/56 kDa/59 kDa/61 kDa/65 kDa
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ID gène
- 54498
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UniProt
- Q9NWM0
Antigène
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