SOAT1 anticorps (AA 1-130)

N° du produit ABIN6148259

Cet anticorps Lapin Polyclonal détecte spécifiquement SOAT1 dans WB et IF. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour SOAT1 anticorps (AA 1-130) (ABIN6148259)

Antigène: SOAT1 (Sterol O-Acyltransferase 1 (SOAT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOAT1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-SOAT1 anticorps

Épitope: AA 1-130

Séquence: MVGEEKMSLR NRLSKSRENP EEDEDQRNPA KESLETPSNG RIDIKQLIAK KIKLTAEAEE LKPFFMKEVG SHFDDFVTNL IEKSASLDNG GCALTTFSVL EGEKNNHRAK DLRAPPEQGK IFIARRSLLD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human SOAT1 (NP_003092.4).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-SOAT1 (ABIN6148259)

Hai, Ritchey, Robinet, Alzayed, Brubaker, Zhang, Smith: "Quantitative Trait Locus Mapping of Macrophage Cholesterol Metabolism and CRISPR/Cas9 Editing Implicate an ACAT1 Truncation as a Causal Modifier Variant." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 1, pp. 83-91, (2019) (PubMed).

Détails sur SOAT1

Antigène: SOAT1 (Sterol O-Acyltransferase 1 (SOAT1))

Autre désignation: SOAT1

Sujet: The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene.,SOAT1,ACACT,ACAT,ACAT-1,ACAT1,SOAT,STAT,Cancer,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Heart,Lipids,Lipoproteins/Apolipoproteins,Cardiovascular diseases,Heart disease,SOAT1

Poids moléculaire: 57 kDa/58 kDa/64 kDa

ID gène: 6646

UniProt: P35610