SPTA1 anticorps (AA 940-1160)

N° du produit ABIN6148401

Cet anticorps Lapin Polyclonal détecte spécifiquement SPTA1 dans WB, IHC et IF. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour SPTA1 anticorps (AA 940-1160) (ABIN6148401)

Antigène: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPTA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SPTA1 anticorps

Épitope: AA 940-1160

Séquence: KHEAFLLDLN SFGDSMKALR NQANACQQQQ AAPVEGVAGE QRVMALYDFQ ARSPREVTMK KGDVLTLLSS INKDWWKVEA ADHQGIVPAV YVRRLAHDEF PMLPQRRREE PGNITQRQEQ IENQYRSLLD RAEERRRRLL QRYNEFLLAY EAGDMLEWIQ EKKAENTGVE LDDVWELQKK FDEFQKDLNT NEPRLRDINK VADDLLFEGL LTPEGAQIRQ E

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 940-1160 of human alpha 1 Spectrin (NP_003117.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-SPTA1 (ABIN6148401)

Talhouarne, Gall: "7SL RNA in vertebrate red blood cells." dans: RNA (New York, N.Y.), Vol. 24, Issue 7, pp. 908-914, (2018) (PubMed).

Détails sur SPTA1

Antigène: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Autre désignation: SPTA1

Sujet: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.,SPTA1,EL2,HPP,HS3,SPH3,SPTA,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Cardiovascular,Blood,Blood Cell Antigens,SPTA1

Poids moléculaire: 279 kDa/280 kDa

ID gène: 6708

UniProt: P02549

Pathways: Regulation of Actin Filament Polymerization