SULF1 anticorps (AA 400-700)
Aperçu rapide pour SULF1 anticorps (AA 400-700) (ABIN6148697)
Antigène
Voir toutes SULF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 400-700
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Séquence
- TNKKAKIWRD TFLVERGKFL RKKEESSKNI QQSNHLPKYE RVKELCQQAR YQTACEQPGQ KWQCIEDTSG KLRIHKCKGP SDLLTVRQST RNLYARGFHD KDKECSCRES GYRASRSQRK SQRQFLRNQG TPKYKPRFVH TRQTRSLSVE FEGEIYDINL EEEEELQVLQ PRNIAKRHDE GHKGPRDLQA SSGGNRGRML ADSSNAVGPP TTVRVTHKCF ILPNDSIHCE RELYQSARAW KDHKAYIDKE IEALQDKIKN LREVRGHLKR RKPEECSCSK QSYYNKEKGV KKQEKLKSHL H
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Réactivité croisée
- Humain, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human SULF1 (NP_055985.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SULF1 (Sulfatase 1 (SULF1))
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Autre désignation
- SULF1
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Sujet
- This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants.,SULF1,SULF-1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,SULF1
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Poids moléculaire
- 101 kDa
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ID gène
- 23213
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UniProt
- Q8IWU6
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Pathways
- EGFR Signaling Pathway
Antigène
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