APOH anticorps
Aperçu rapide pour APOH anticorps (ABIN614872)
Antigène
Voir toutes APOH AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody recognizes beta2GP-I. A single precipitin arc is observed with normal plasma. No arc was seen with beta2GP-I deficient plasma.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, porcine, rat, rabbit, canine
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Purification
- Immunoaffinity chromatography
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Immunogène
- Human beta2-Glycoprotein-I (beta2GP-I) purified from plasma Genename: APOH
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 2.0 mg/mL
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Buffer
- 10 mM HEPES, pH 7.4, 0.15 M sodium chloride, 50 % glycerol
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))
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Autre désignation
- Apolipoprotein H (Apo H)
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Sujet
- Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.Synonyms: APC Inhibitor, Anticardiolipin Cofactor, Apo-H, ApoH, B2G1, B2GPI, Beta-2-glycoprotein I, Beta2GPI
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ID gène
- 350
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NCBI Accession
- NP_000033
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UniProt
- P02749
Antigène
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