TAPBP anticorps (AA 30-260)
Aperçu rapide pour TAPBP anticorps (AA 30-260) (ABIN6148848)
Antigène
Voir toutes TAPBP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 30-260
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Séquence
- VEDASGKGLA KRPGALLLRQ GPGEPPPRPD LDPELYLSVH DPAGALQAAF RRYPRGAPAP HCEMSRFVPL PASAKWASGL TPAQNCPRAL DGAWLMVSIS SPVLSLSSLL RPQPEPQQEP VLITMATVVL TVLTHTPAPR VRLGQDALLD LSFAYMPPTS EAASSLAPGP PPFGLEWRRQ HLGKGHLLLA ATPGLNGQMP AAQEGAVAFA AWDDDEPWGP WTGNGTFWLP T
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 30-260 of human TAPBP (NP_757345.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
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Autre désignation
- TAPBP
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Sujet
- This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.,TAPBP,NGS17,TAPA,TPN,TPSN,tapasin,Signal Transduction,Immunology & Inflammation,TAPBP
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Poids moléculaire
- 38 kDa/43 kDa/47 kDa/53 kDa
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ID gène
- 6892
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UniProt
- O15533
Antigène
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