TBL1XR1 anticorps (AA 1-180)

N° du produit ABIN6148893

Cet anticorps anti-TBL1XR1 est un anticorps Lapin Polyclonal détectant TBL1XR1 dans WB et IF. Adapté pour Humain.

Aperçu rapide pour TBL1XR1 anticorps (AA 1-180) (ABIN6148893)

Antigène: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBL1XR1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-TBL1XR1 anticorps

Épitope: AA 1-180

Séquence: MSISSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GALVPPAALI SIIQKGLQYV EAEVSINEDG TLFDGRPIES LSLIDAVMPD VVQTRQQAYR DKLAQQQAAA AAAAAAAASQ QGSAKNGENT ANGEENGAHT IANNHTDMME VDGDVEIPPN KAVVLRGHES EVFICAWNPV

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human TBL1XR1 (NP_078941.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TBL1XR1

Antigène: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Autre désignation: TBL1XR1

Sujet: This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.,TBL1XR1,C21,DC42,IRA1,MRD41,TBLR1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Notch Signaling Pathway,Endocrine & Metabolism,Lipid Metabolism,TBL1XR1

Poids moléculaire: 55 kDa

ID gène: 79718

UniProt: Q9BZK7

Pathways: Regulation of Lipid Metabolism by PPARalpha