TDRKH anticorps (AA 36-355)
Aperçu rapide pour TDRKH anticorps (AA 36-355) (ABIN6148980)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 36-355
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Séquence
- RYRESREERL TFVGEDDIEI EMRVPQEAVK LIIGRQGANI KQLRKQTGAR IDVDTEDVGD ERVLLISGFP VQVCKAKAAI HQILTENTPV SEQLSVPQRS VGRIIGRGGE TIRSICKASG AKITCDKESE GTLLLSRLIK ISGTQKEVAA AKHLILEKVS EDEELRKRIA HSAETRVPRK QPISVRREDM TEPGGAGEPA LWKNTSSSME PTAPLVTPPP KGGGDMAVVV SKEGSWEKPS DDSFQKSEAQ AIPEMPMFEI PSPDFSFHAD EYLEVYVSAS EHPNHFWIQI VGSRSLQLDK LVNEMTQHYE NSVPEDLTVH
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 36-355 of human TDRKH (NP_001077432.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TDRKH (Tudor and KH Domain Containing (TDRKH))
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Autre désignation
- TDRKH
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Sujet
- Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules.,TDRKH,TDRD2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,TDRKH
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Poids moléculaire
- 57 kDa/62 kDa
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ID gène
- 11022
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UniProt
- Q9Y2W6
Antigène
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