Tescalcin anticorps (AA 135-214)
Aperçu rapide pour Tescalcin anticorps (AA 135-214) (ABIN6149009)
Antigène
Voir toutes Tescalcin (TESC) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 135-214
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Séquence
- YRNVVEELLS GNPHIEKESA RSIADGAMME AASVCMGQME PDQVYEGITF EDFLKIWQGI DIETKMHVRF LNMETMALCH
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Réactivité croisée
- Humain
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 135-214 of human TESC (NP_060369.3).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Tescalcin (TESC)
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Autre désignation
- TESC
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Sujet
- Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+/H(+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.,TESC,CHP3,TSC,tescalcin,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Neuroscience,Calcium Signaling,TESC
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Poids moléculaire
- 18 kDa/21 kDa/24 kDa
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ID gène
- 54997
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UniProt
- Q96BS2
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Pathways
- Proton Transport
Antigène
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