CPT1A anticorps (Internal Region)
Aperçu rapide pour CPT1A anticorps (Internal Region) (ABIN614906)
Antigène
Voir toutes CPT1A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Séquence
- C-DPAQTVEQRL KLFK
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Specificité
- This antibody detects CPT1A / CPT1-L (Internal).
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Immunoaffinity chromatography
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Immunogène
- Synthetic peptide from an internal region of human CPT1A Genename: CPT1A
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline buffer, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
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Autre désignation
- CPT1A / CPT1-L
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Sujet
- The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.Synonyms: Carnitine O-palmitoyltransferase 1 liver isoform, Carnitine palmitoyltransferase 1A
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ID gène
- 1374
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NCBI Accession
- NP_001027017
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UniProt
- P50416
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Pathways
- AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
Antigène
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