TRIAP1 anticorps (AA 1-76)
Aperçu rapide pour TRIAP1 anticorps (AA 1-76) (ABIN6149492)
Antigène
Voir toutes TRIAP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-76
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Séquence
- MNSVGEACTD MKREYDQCFN RWFAEKFLKG DSSGDPCTDL FKRYQQCVQK AIKEKEIPIE GLEFMGHGKE KPENSS
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Réactivité croisée
- Humain
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human TRIAP1 (NP_057483.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))
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Autre désignation
- TRIAP1
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Sujet
- Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA between liposomes (in vitro and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo. Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis.,TRIAP1,HSPC132,MDM35,P53CSV,WF-1,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,TRIAP1
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Poids moléculaire
- 8 kDa
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ID gène
- 51499
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UniProt
- O43715
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Antigène
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