TXNRD2 anticorps (AA 100-310)
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- Antigène Voir toutes TXNRD2 Anticorps
- TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))
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Épitope
- AA 100-310
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TXNRD2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Séquence
- AALLGGLIQD APNYGWEVAQ PVPHDWRKMA EAVQNHVKSL NWGHRVQLQD RKVKYFNIKA SFVDEHTVCG VAKGGKEILL SADHIIIATG GRPRYPTHIE GALEYGITSD DIFWLKESPG KTLVVGASYV ALECAGFLTG IGLDTTIMMR SIPLRGFDQQ MSSMVIEHMA SHGTRFLRGC APSRVRRLPD GQLQVTWEDS TTGKEDTGTF D
- Réactivité croisée
- Humain, Souris
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 100-310 of human Thioredoxin reductase 2 (Thioredoxin reductase 2 (TXNRD2 ) ) (NP_006431.2).
- Isotype
- IgG
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Commentaires
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))
- Autre désignation
- TXNRD2 (TXNRD2 Produits)
- Synonymes
- anticorps CG11401, anticorps Dm-TrxR, anticorps DmTrx, anticorps DmTrxR-2, anticorps Dmel\\CG11401, anticorps Trxr2, anticorps trxr-2, anticorps SELZ, anticorps TR, anticorps TR-BETA, anticorps TR3, anticorps TRXR2, anticorps AA118373, anticorps ESTM573010, anticorps TGR, anticorps Tr3, anticorps Trxrd2, anticorps thioredoxin reductase 2, anticorps Trxr-2, anticorps TXNRD2, anticorps Txnrd2
- Sujet
- The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms, including a few localized in the cytosol and some lacking the C-terminal Sec residue, have been found for this gene.,TXNRD2,SELZ,TR,TR-BETA,TR3,TRXR2,Cell Biology & Developmental Biology,Endocrine & Metabolism,TXNRD2
- Poids moléculaire
- 30 kDa/46 kDa/53 kDa/56 kDa
- ID gène
- 10587
- UniProt
- Q9NNW7
- Pathways
- Cell RedoxHomeostasis
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