UBE2F anticorps (AA 1-185)

N° du produit ABIN6149794

Détail du produit anti-UBE2F anticorps

Antigène: UBE2F (Ubiquitin-Conjugating Enzyme E2F (UBE2F))

Épitope: AA 1-185

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2F est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MLTLASKLKR DDGLKGSRTA ATASDSTRRV SVRDKLLVKE VAELEANLPC TCKVHFPDPN KLHCFQLTVT PDEGYYQGGK FQFETEVPDA YNMVPPKVKC LTKIWHPNIT ETGEICLSLL REHSIDGTGW APTRTLKDVV WGLNSLFTDL LNFDDPLNIE AAEHHLRDKE DFRNKVDDYI KRYAR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human UBE2F (NP_542409.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur UBE2F

Antigène: UBE2F (Ubiquitin-Conjugating Enzyme E2F (UBE2F))

Autre désignation: UBE2F (UBE2F Produits)

Synonymes: anticorps NCE2, anticorps 2510010F15Rik, anticorps AI851109, anticorps RGD1307608, anticorps zgc:77005, anticorps ubiquitin conjugating enzyme E2 F (putative), anticorps NEDD8-conjugating enzyme UBE2F, anticorps ubiquitin-conjugating enzyme E2F (putative), anticorps ubiquitin conjugating enzyme E2F (putative) S homeolog, anticorps UBE2F, anticorps Tsp_01616, anticorps ube2f, anticorps ube2f.S, anticorps Ube2f

Sujet: Ube2F is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for conjugation of Nedd8 to protein substrates. Neddylation is initiated by activating Nedd8 by the Nedd8 activating enzyme APPBP1/UBA3. Cullin is a well-known substrate for Neddylation. When NEDD8 is covalently bonded to the CRL, it stimulates its E3 Ub ligase activity. A new approach to cancer therapy involves hindering the Nedd8 conjugation pathway through inhibition of the NAE1/UBA3 enzyme.,UBE2F,NCE2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,UBE2F

Poids moléculaire: 11 kDa/13 kDa/17 kDa/18 kDa/21 kDa/23 kDa

ID gène: 140739

UniProt: Q969M7