ULBP2 anticorps (AA 26-216)
Aperçu rapide pour ULBP2 anticorps (AA 26-216) (ABIN6149919)
Antigène
Voir toutes ULBP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 26-216
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Séquence
- GRADPHSLCY DITVIPKFRP GPRWCAVQGQ VDEKTFLHYD CGNKTVTPVS PLGKKLNVTT AWKAQNPVLR EVVDILTEQL RDIQLENYTP KEPLTLQARM SCEQKAEGHS SGSWQFSFDG QIFLLFDSEK RMWTTVHPGA RKMKEKWEND KVVAMSFHYF SMGDCIGWLE DFLMGMDSTL EPSAGAPLAM S
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Réactivité croisée
- Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 26-216 of human ULBP2 (NP_079493.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- ULBP2 (UL16 Binding Protein 2 (ULBP2))
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Autre désignation
- ULBP2
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Sujet
- This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6.,ULBP2,ALCAN-alpha,N2DL2,NKG2DL2,RAET1H,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,ULBP2
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Poids moléculaire
- 27 kDa
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ID gène
- 80328
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UniProt
- Q9BZM5
Antigène
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