Vinculin anticorps (AA 767-1066)

N° du produit ABIN6150070

L’anticorps Lapin Polyclonal anti-Vinculin a été validé pour WB, IHC et IF. Il convient pour détecter Vinculin dans des échantillons de Humain.

Aperçu rapide pour Vinculin anticorps (AA 767-1066) (ABIN6150070)

Antigène: Vinculin (VCL)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Vinculin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Vinculin anticorps

Épitope: AA 767-1066

Séquence: AKREVENSED PKFREAVKAA SDELSKTISP MVMDAKAVAG NISDPGLQKS FLDSGYRILG AVAKVREAFQ PQEPDFPPPP PDLEQLRLTD ELAPPKPPLP EGEVPPPRPP PPEEKDEEFP EQKAGEVINQ PMMMAARQLH DEARKWSSKG NDIIAAAKRM ALLMAEMSRL VRGGSGTKRA LIQCAKDIAK ASDEVTRLAK EVAKQCTDKR IRTNLLQVCE RIPTISTQLK ILSTVKATML GRTNISDEES EQATEMLVHN AQNLMQSVKE TVREAEAASI KIRTDAGFTL RWVRKTPWYQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 767-1066 of human Vinculin (NP_003364.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Vinculin

Antigène: Vinculin (VCL)

Autre désignation: VCL

Sujet: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.,VCL,CMD1W,CMH15,HEL114,MV,MVCL,vinculin,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,Cardiovascular,Heart,Contractility,Cardiac arrhythmias,VCL

Poids moléculaire: 24 kDa/116 kDa/123 kDa

ID gène: 7414

UniProt: P18206

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2