OPTN anticorps (AA 575-591)
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- Antigène Voir toutes OPTN Anticorps
- OPTN (Optineurin (OPTN))
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Épitope
- AA 575-591
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp OPTN est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody reacts to Optineurin (OPTN).
- Purification
- Immunoaffinity Chromatography
- Immunogène
- OPTN antibody was raised against synthetic peptide corresponding to aa 575-591 (G575EVLPDIDTLQIHVMDC591) of human, mouse and rat optineurin (FIP-2 (14.7K interacting protein-2), NRP (nemo-related protein)). Genename: OPTN
- Top Product
- Discover our top product OPTN Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- TBS, pH 7.4 containing 0.5 mg/mL BSA, 0.02 % sodium azide, 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- OPTN (Optineurin (OPTN))
- Autre désignation
- Optineurin / HIP7 (OPTN Produits)
- Synonymes
- anticorps nrp, anticorps fip2, anticorps hip7, anticorps hypl, anticorps glc1e, anticorps tfiiia-intp, anticorps ALS12, anticorps FIP2, anticorps GLC1E, anticorps HIP7, anticorps HYPL, anticorps NRP, anticorps TFIIIA-INTP, anticorps Fip2, anticorps 4930441O07Rik, anticorps fj52f04, anticorps si:ch211-240l19.3, anticorps wu:fj52f04, anticorps zgc:66386, anticorps zgc:77868, anticorps optineurin, anticorps optineurin L homeolog, anticorps OPTN, anticorps optn, anticorps Optn, anticorps optn.L
- Sujet
- Optineurin (OTPN), a coiled-coil containing protein, may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.Synonyms: E3-14.7K-interacting protein, FIP-2, FIP2, GLC1E, HYPL, Huntingtin yeast partner L, Huntingtin-interacting protein 7, Huntingtin-interacting protein L, NEMO-related protein, NRP, Optic neuropathy-inducing protein, Transcription factor IIIA-interacting protein
- ID gène
- 10133
- NCBI Accession
- NP_001008212
- UniProt
- Q96CV9
- Pathways
- M Phase
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