ACE2 anticorps (N-Term)

N° du produit ABIN615244

Cet anticorps Lapin Polyclonal détecte spécifiquement ACE2 dans WB, IHC (p) et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour ACE2 anticorps (N-Term) (ABIN615244)

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACE2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-ACE2 anticorps

Épitope: N-Term

Specificité: This antibody reacts to Angiotensin I Converting Enzyme 2 (ACE2).

Purification: Immunoaffinity Chromatography

Immunogène: ACE2 antibody was raised against synthetic peptide

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur ACE2

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Autre désignation: ACE2

Sujet: Angiotensin-Converting Enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.Synonyms: ACE-related carboxypeptidase, Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog

ID gène: 59272

NCBI Accession: NP_068576

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour