PAR1 anticorps (Internal Region)

N° du produit ABIN615450

Cet anticorps anti-PAR1 Polyclonal Chèvre (ABIN615450) détecte spécifiquement PAR1 dans WB, IHC (p) et EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PAR1 anticorps (Internal Region) (ABIN615450)

Antigène: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PAR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-PAR1 anticorps

Épitope: Internal Region

Séquence: C-TRARRPESKA TNAT

Specificité: This antibody detects Thrombin receptor / F2R.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide from the Internal region (near N-terminus) of the human protein sequence according to NP_001983.2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PAR1

Antigène: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Autre désignation: Thrombin Receptor / F2R

Sujet: Thrombin Receptor is a Proteinase-Activated Receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. Thrombin induced RANTES expression through a PAR-1 mediated pathway influences inflammatory cell migration to the synovium in patients with rheumatoid arthritis.Synonyms: CF2R, Coagulation factor II receptor, PAR-1, PAR1, Proteinase-activated receptor 1

ID gène: 2149

NCBI Accession: NP_001983

UniProt: P25116

Pathways: Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus