Coagulation Factor X anticorps
Aperçu rapide pour Coagulation Factor X anticorps (ABIN615558)
Antigène
Voir toutes Coagulation Factor X (F10) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects Coagulation factor X (F10). Only one arc was seen with normal plasma. No arc was seen with Factor X deficient plasma.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Immunoaffinity Chromatography
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Immunogène
- Human Factor X purified from plasma, activated and active site blocked
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- 10 mM HEPES, pH 7.4, 0.15 M Sodium Chloride, 50 % Glycerol
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Coagulation Factor X (F10)
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Sujet
- F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.Synonyms: Stuart factor, Stuart-Prower factor
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ID gène
- 2159
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NCBI Accession
- NP_000495
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UniProt
- P00742
Antigène
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