SELPLG anticorps (CF®640R)

N° du produit ABIN6157941

Détail du produit anti-SELPLG anticorps (CF®640R)

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SELPLG est conjugé à/à la CF®640R

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunostaining (ISt)

Fonction: Mouse Monoclonal anti-CD162 (PSGL1/1601), CF640R Conjugate

Attributs du produit: CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human full-length SELPLG (CD162) protein

Clone: PSGL1-1601

Isotype: IgG1

Information d'application

Indications d'application: Immunohistology (formalin) 1-2 μg/mL

• Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris, 1 mM EDTA  pH 9.0 for 10-20 min followed by cooling at RT for 20 min
• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

Jurkat cells. Tonsil or Spleen

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur SELPLG

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Autre désignation: CD162 (SELPLG Produits)

Synonymes: anticorps CD162, anticorps CLA, anticorps PSGL-1, anticorps PSGL1, anticorps SELPLG, anticorps SELPG, anticorps Psgl-1, anticorps Psgl1, anticorps Selp1, anticorps Selpl, anticorps selectin P ligand, anticorps selectin, platelet (p-selectin) ligand, anticorps clasper, anticorps SELPLG, anticorps Selplg, anticorps cla

Sujet: CD162, CLA, Cutaneous lymphocyte associated antigen, P-selectin glycoprotein lig, 1, PSGL1, Selectin P lig, SELPLG

Poids moléculaire: 43-120 kDa

ID gène: 6404, 591014

UniProt: Q14242