CD7 anticorps (CF®405S)

N° du produit ABIN6160217

Cet anticorps anti-CD7 est un anticorps Souris Monoclonal détectant CD7 dans FACS et IF. Adapté pour Humain, Cobaye et Porc.

Aperçu rapide pour CD7 anticorps (CF®405S) (ABIN6160217)

Antigène: CD7

Reactivité: Humain, Cobaye, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD7 est conjugé à/à la CF®405S

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: B-F12

Détail du produit anti-CD7 anticorps (CF®405S)

Fonction: Mouse Monoclonal anti-CD7 (B-F12), CF405S Conjugate

Attributs du produit: This antibody recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Chronic Lymphoid Leukemia cells (CLL)

Isotype: IgG2a kappa

Information d'application

Indications d'application: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

Jurkat, HUT-78, Molt-4, CEM cells, or human peripheral blood lymphocytes. Lymph node and tonsil.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur CD7

Antigène: CD7

Autre désignation: CD7

Sujet: GP40, Leu9, p41, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41

Poids moléculaire: 40 kDa

ID gène: 924, 186820

UniProt: P09564

Pathways: Cell-Cell Junction Organization