IL-10RA anticorps (pSer319, pSer323)

N° du produit ABIN616045

Cet anticorps Lapin Polyclonal détecte spécifiquement IL-10RA dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour IL-10RA anticorps (pSer319, pSer323) (ABIN616045)

Antigène: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-10RA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL-10RA anticorps

Épitope: pSer319, pSer323

Séquence: D-S(p)-G-F-G-S(p)-T

Specificité: This antibody detects endogenous level of IL-10R subunit alpha protein only when phosphorylated at serine 319 and serine 323.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity-chromatography using epitope-specific peptide

Immunogène: Peptide sequence around phosphorylation site of Serine 319/Serine 323 derived from Human IL-10R subunit alpha.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store (in aliquots) at -20 °C.

Détails sur IL-10RA

Antigène: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Autre désignation: CDw210a / IL10RA

Sujet: Defects in IL10RA are the cause of inflammatory bowel disease type 28 (IBD28) [MIM:613148]. It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous, it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers, fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints.Synonyms: IL-10R-A, IL10 Receptor alpha, Interleukin-10 receptor alpha chain

Poids moléculaire: 63 kDa

ID gène: 3587

NCBI Accession: NP_001549

UniProt: Q13651

Pathways: Growth Factor Binding