hCG Intact anticorps (CF®568)

N° du produit ABIN6165779

Cet anticorps anti-hCG Intact est un anticorps Monoclonal produit chez le Souris, détectant hCG Intact dans IHC (f). Convient pour Humain.

Aperçu rapide pour hCG Intact anticorps (CF®568) (ABIN6165779)

Antigène: hCG Intact

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: CF®568

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: HCGab-52

Détail du produit

Fonction: Mouse Monoclonal anti-HCG intact (HCGab/52), CF568 Conjugate

Attributs du produit: This MAb is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the ? ? and ? ? subunits. The ? ? subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90 % and 60 % of cases respectively. 20 % of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Purified hCG protein

Isotype: IgG1 kappa

Information d'application

Indications d'application: Immunohistology formalin-fixed 0.5-1 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
• Optimal dilution for a specific application should be determined by user

Commentaires:

JAR or TT Cells. Placenta

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détail du antigène

Antigène: hCG Intact

Poids moléculaire: ~35 kDa (intact hCG)

ID gène: 1081, 1082