CD2 anticorps (Biotin)

N° du produit ABIN616779

Cet anticorps anti-CD2 Monoclonal Souris conjugué à Biotin (Clone MEM-65) (ABIN616779) détecte spécifiquement CD2 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD2 anticorps (Biotin) (ABIN616779)

Antigène: CD2

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD2 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: MEM-65

Détail du produit anti-CD2 anticorps (Biotin)

Specificité: This antibody recognizes an unique epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T-lymphocytes and NK cells, also expressed by all thymocytes.

Réactivité croisée (Details): Species reactivity (tested):Human

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur CD2

Antigène: CD2

Autre désignation: CD2

Sujet: CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Morover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.Synonyms: Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5

ID gène: 914