CD7 anticorps (APC)
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- Antigène Voir toutes CD7 Anticorps
- CD7
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD7 est conjugé à/à la APC
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Application
- Flow Cytometry (FACS)
- Specificité
- This antibody reacts with CD7, a 40 kDa type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.
- Réactivité croisée (Details)
- Species reactivity (tested):Human
- Clone
- MEM-186
- Isotype
- IgG1
- Top Product
- Discover our top product CD7 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Antigène
- CD7
- Autre désignation
- CD7 (CD7 Produits)
- Synonymes
- anticorps GP40, anticorps LEU-9, anticorps TP41, anticorps Tp40, anticorps CD7 molecule, anticorps CD7 antigen, anticorps Cd7 molecule, anticorps CD7, anticorps Cd7
- Sujet
- CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.Synonyms: GP40, Leu-9, T-cell leukemia antigen, TP41
- ID gène
- 924
- Pathways
- Cell-Cell Junction Organization
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