CD52 anticorps (APC)
Aperçu rapide pour CD52 anticorps (APC) (ABIN616802)
Antigène
Voir toutes CD52 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody reacts with Human CD52 (CAMPATH-1), a 21-28 kDa glycoprotein containing a large N-linked carbohydrate moiety, mature CD52 Molecule is actually much smaller (approx. 8-9 kDa). CD52 is expressed at high levels on lymphocytes, monocytes/macrophages and in male reproductive tract.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Size-Exclusion Chromatography
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Isotype
- IgG2b
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS, 15 mM Sodium Azide, 0.2 % (w/v) high-grade protease free BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- CD52
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Autre désignation
- CD52 / CAMPATH-1
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Sujet
- CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5
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ID gène
- 1043
Antigène
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