VLDLR anticorps (C-Term) (CF®568)

N° du produit ABIN6168173

Cet anticorps anti-VLDLR est un anticorps Souris Monoclonal détectant VLDLR dans WB, IHC, FACS, IF et ISt. Adapté pour Humain et Rat.

Aperçu rapide pour VLDLR anticorps (C-Term) (CF®568) (ABIN6168173)

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VLDLR est conjugé à/à la CF®568

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunostaining (ISt)

Clone: VLDLR-1337

Détail du produit anti-VLDLR anticorps (CF®568)

Épitope: C-Term

Fonction: Mouse Monoclonal anti-VLDL Receptor (VLDLR/1337), CF568 Conjugate

Attributs du produit: VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human VLDLR fragment from c-terminal (exact sequence is proprietary)

Isotype: IgG1

Information d'application

Indications d'application: Immunohistology (formalin) 1-2 μg/mL

• Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris, 1 mM EDTA  pH 9.0 for 10-20 min followed by cooling at RT for 20 min
• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

HeLa or U-251 cells. Pancreas, Cerebellum, Heart or Skeletal Muscle.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur VLDLR

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Autre désignation: VLDL Receptor

Sujet: Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR

Poids moléculaire: 143-161 kDa

ID gène: 7436

Pathways: Cellular Response to Molecule of Bacterial Origin