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Keratin 10 anticorps (CF®405S)

KRT10 Reactivité: Humain FACS, IHC, IF Hôte: Souris Monoclonal KRT10-1275 CF®405S
N° du produit ABIN6172284
  • Antigène Voir toutes Keratin 10 (KRT10) Anticorps
    Keratin 10 (KRT10)
    Reactivité
    • 121
    • 57
    • 50
    • 27
    • 18
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 75
    • 49
    • 2
    Souris
    Clonalité
    • 68
    • 58
    Monoclonal
    Conjugué
    • 72
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Keratin 10 est conjugé à/à la CF®405S
    Application
    • 80
    • 56
    • 53
    • 39
    • 34
    • 27
    • 15
    • 14
    • 13
    • 11
    • 11
    • 8
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Fonction
    Mouse Monoclonal anti-Cytokeratin 10 (KRT10/1275), CF405S Conjugate
    Attributs du produit
    This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    Immunogène
    Recombinant human KRT10 protein
    Clone
    KRT10-1275
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product KRT10 Anticorps primaire
  • Indications d'application
    Flow cytometry 0.5-1 μg/million cells in 0.1 mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer  pH 6.0for 10-20 min followed by cooling at RT for 20 min
    • Immunofluorescence 0.5-1 μg/mL Immunohistology (formalin) 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user
    Commentaires

    A431, HeLa, MCF7 cells. Esophagus or tonsil.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100 μg/mL
    Buffer
    PBS/0.1 % BSA/0.05 % azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Protect from light
  • Antigène
    Keratin 10 (KRT10)
    Autre désignation
    Cytokeratin 10 (KRT10 Produits)
    Synonymes
    anticorps BCIE, anticorps BIE, anticorps CK10, anticorps EHK, anticorps K10, anticorps KPP, anticorps D130054E02Rik, anticorps K1C1, anticorps Krt-1.10, anticorps Krt1-10, anticorps Ka10, anticorps Ker10, anticorps KRT10, anticorps KRT25, anticorps KRT27, anticorps KRT28, anticorps keratin 10, anticorps keratin 10, type I S homeolog, anticorps keratin, type I cytoskeletal 25, anticorps KRT10, anticorps Krt10, anticorps krt10.S, anticorps LOC101085587
    Sujet
    BCIE, BIE, EHK, Keratin Type I Cytoskeletal 10, KRT10
    Poids moléculaire
    56.5 kDa
    ID gène
    3858, 99936
    UniProt
    P13645
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