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KRT14 anticorps (C-Term) (CF®568)

KRT14 Reactivité: Humain, Rat, Souris IF, FACS, IHC (f) Hôte: Souris Monoclonal LL002 CF®568
N° du produit ABIN6172564
  • Antigène Voir toutes KRT14 Anticorps
    KRT14 (Keratin 14 (KRT14))
    Épitope
    • 23
    • 15
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 92
    • 59
    • 45
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 66
    • 30
    • 1
    Souris
    Clonalité
    • 54
    • 43
    Monoclonal
    Conjugué
    • 56
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KRT14 est conjugé à/à la CF®568
    Application
    • 38
    • 28
    • 24
    • 23
    • 21
    • 16
    • 13
    • 13
    • 11
    • 10
    • 8
    • 5
    • 2
    • 2
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Fonction
    Mouse Monoclonal anti-Cytokeratin 14 (LL002), CF568 Conjugate
    Attributs du produit
    Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    Immunogène
    A synthetic peptide of 15 amino acid from the C-terminus of human keratin 14.
    Clone
    LL002
    Isotype
    IgG3
    Top Product
    Discover our top product KRT14 Anticorps primaire
  • Indications d'application
    Immunohistology formalin-fixed 0.5-1.0 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    Commentaires

    A431 cells. Skin or Squamous cell carcinoma

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100 μg/mL
    Buffer
    PBS/0.1 % BSA/0.05 % azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Protect from light
  • Antigène
    KRT14 (Keratin 14 (KRT14))
    Autre désignation
    Cytokeratin 14 (KRT14 Produits)
    Synonymes
    anticorps CK14, anticorps EBS3, anticorps EBS4, anticorps K14, anticorps NFJ, anticorps AI626930, anticorps Krt-1.14, anticorps Krt1-14, anticorps Ka14, anticorps ouro2, anticorps keratin 14, anticorps keratin 14, type I L homeolog, anticorps KRT14, anticorps Krt14, anticorps krt14.L
    Sujet
    CK-14, Dowling Meara, ebs3, ebs4, Epidermolysis Bullosa Simplex, k14, Keratin 14, Keratin Type I Cytoskeletal 14, Koebner, krt14, NFJ
    Poids moléculaire
    ~50 kDa
    ID gène
    3861, 6545380
    UniProt
    P02533
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