RBP1 anticorps (CF®594)

N° du produit ABIN6172688

Cet anticorps anti-RBP1 est un anticorps Souris Monoclonal détectant RBP1 dans IF et IHC (f). Adapté pour Humain, Souris, Rat, Lapin, Singe, Chévre et Chimpanzé.

Aperçu rapide pour RBP1 anticorps (CF®594) (ABIN6172688)

Antigène: RBP1 (Retinol Binding Protein 1, Cellular (RBP1))

Reactivité: Humain, Souris, Rat, Lapin, Singe, Chévre, Chimpanzé

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RBP1 est conjugé à/à la CF®594

Application: Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: G4E4

Détail du produit anti-RBP1 anticorps (CF®594)

Fonction: Mouse Monoclonal anti-Retinol Binding Protein 1 (G4E4), CF594 Conjugate

Attributs du produit: This MAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Retinol binding protein-1 purified from human plasma

Isotype: IgG1 kappa

Information d'application

Indications d'application: Immunohistology formalin-fixed 0.5-1 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

Hepatic or ovarian carcinoma

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur RBP1

Antigène: RBP1 (Retinol Binding Protein 1, Cellular (RBP1))

Autre désignation: Retinol Binding Protein 1

Poids moléculaire: 21-25 kDa

ID gène: 5947, 5948, 5950

UniProt: P02753